PA32540 Cuts Gastric Acid Faster Than Enteric-Coated Aspirin
SAN DIEGO - The investigational compound PA32540 provides faster gastric protection than enteric-coated omeprazole 40 mg, researchers announced at Digestive Disease Week 2012. PA32540 is an investigational coordinated-delivery tablet of immediate-release (IR) omeprazole (40 mg), a proton pump inhibitor (PPI), layered around enteric-coated aspirin (325 mg). The product was developed to provide the cardiovascular benefits of aspirin in patients at risk for aspirin-associated ulcers...

Molecule That Prevents Heart Damage is Also Proving Its Worth In Diabetic Patients
ACE2, a molecule that has been shown to prevent damage in the heart, is now proving to be protective of the major organs that are often damaged in diabetic patients. Gavin Oudit, a researcher with the Faculty of Medicine & Dentistry, and his colleagues at the University of Florida, found that lab models that lacked ACE2 had worse cardiovascular complications related to diabetes. "We show that if you take ACE2 away, they [lab models of diabetes] do very poorly," said Oudit. "It worsened their heart function and their vascular function...